BIOL 416 Cancer and Cell Biology

Exploration of cell and subcellular structure and function, emphasizing mechanisms leading to neoplasia and progression to malignancy and metastasis. Topics include protein sorting, vesicular trafficking, and protein degradation; signal transduction pathways and oncogenes; cell cycle regulation, apoptosis, and tumor suppressor genes; and complex heterogeneous tumor-stromal interactions. Laboratory highlights techniques of cell culture, protein immunodetection, subcellular localization, fluorescence microscopy, and histotechnology.